Synthesis and Spectral Characterization of 4-Hydroxy-3- Methoxybenzaldehyde Derivatives
Vanillin plays an important role in flavouring and as aroma agent. Vanillin has been used as a chemical intermediate in pharmaceutical and chemical syntheses. Schiff base products have been proved to poses beneficial biological effect towards health. Fourteen vanillin derivatives were synthesized...
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| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Universiti Malaysia Sarawak, (UNIMAS)
2015
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| Subjects: | |
| Online Access: | http://ir.unimas.my/id/eprint/13423/1/Synthesis.pdf http://ir.unimas.my/id/eprint/13423/ http://publisher.unimas.my/ojs/index.php/BJRST |
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| Summary: | Vanillin plays an important role in flavouring and as aroma agent. Vanillin has been used as a chemical
intermediate in pharmaceutical and chemical syntheses. Schiff base products have been proved to poses
beneficial biological effect towards health. Fourteen vanillin derivatives were synthesized via Schiff base
reaction using p-vanillin as the starting material reacted with 2-aminobenzenethiol, furan-2-carbohydrazide, 2-
hydrazinylpyridine, 4-hydroxybenzohydrazide, acetohydrazide, benzohydrazide, (diphenylmethylidene)
hydrazine, pyridine-4-carbohydrazide, benzene-1,2-diamine, phenylhydrazine, 2-hydroxybenzohydrazide, 1,3-
benzothiazol-2-amine, 1-cyclohexylthiourea respectively. All of the compounds were characterized by elemental
analysis, FTIR and 1H NMR. |
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