Synthesis and Spectral Characterization of 4-Hydroxy-3- Methoxybenzaldehyde Derivatives

Vanillin plays an important role in flavouring and as aroma agent. Vanillin has been used as a chemical intermediate in pharmaceutical and chemical syntheses. Schiff base products have been proved to poses beneficial biological effect towards health. Fourteen vanillin derivatives were synthesized...

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主要な著者: Mohd Razip, Asaruddin, Sam, Ezekiel, Mohammad Farhan, Ariffeen, Md Abu, Affan
フォーマット: 論文
言語:English
出版事項: Universiti Malaysia Sarawak, (UNIMAS) 2015
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オンライン・アクセス:http://ir.unimas.my/id/eprint/13423/1/Synthesis.pdf
http://ir.unimas.my/id/eprint/13423/
http://publisher.unimas.my/ojs/index.php/BJRST
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要約:Vanillin plays an important role in flavouring and as aroma agent. Vanillin has been used as a chemical intermediate in pharmaceutical and chemical syntheses. Schiff base products have been proved to poses beneficial biological effect towards health. Fourteen vanillin derivatives were synthesized via Schiff base reaction using p-vanillin as the starting material reacted with 2-aminobenzenethiol, furan-2-carbohydrazide, 2- hydrazinylpyridine, 4-hydroxybenzohydrazide, acetohydrazide, benzohydrazide, (diphenylmethylidene) hydrazine, pyridine-4-carbohydrazide, benzene-1,2-diamine, phenylhydrazine, 2-hydroxybenzohydrazide, 1,3- benzothiazol-2-amine, 1-cyclohexylthiourea respectively. All of the compounds were characterized by elemental analysis, FTIR and 1H NMR.