Nanoscaled PAMAM Dendrimer Spacer Improved the Photothermal-Photodynamic Treatment Efficiency of Photosensitizer-Decorated Confeito-Like Gold Nanoparticles for Cancer Therapy

• Main Authors: Saw, Wen Shang, Anasamy, Theebaa, Do, Thu Thi Anh, Lee, Hong Boon, Chee, Chin Fei, Isci, Umit, Misran, Misni, Dumoulin, Fabienne, Chong, Wu Yi, Kiew, Lik Voon, Imae, Toyoko, Chung, Lip Yong
• 格式: Article
• 出版: John Wiley & Sons 2022
• 主題: QD Chemistry; RM Therapeutics. Pharmacology
• 在線閱讀: http://eprints.um.edu.my/41718/; https://doi.org/10.1002/mabi.202200130

A critical factor in developing an efficient photosensitizer-gold nanoparticle (PS-AuNP) hybrid system with improved plasmonic photosensitization is to allocate a suitable space between AuNPs and PS. Poly(amidoamine) (PAMAM) dendrimer is selected as a spacer between the PS and confeito-like gold nan...