Polymorphisms of cell cycle regulator genes CCND1 G870A and TP53 C215G: Association with colorectal cancer susceptibility risk in a Malaysian population

• المؤلفون الرئيسيون: Mohd Nizam, Zahary, Abdul Aziz, Ahmad Aizat, Gurjeet, Kaur
• التنسيق: مقال
• اللغة: English; English
• منشور في: Spandidos Publications 2015
• الموضوعات: QH301 Biology
• الوصول للمادة أونلاين: http://eprints.unisza.edu.my/6685/1/FH02-FSK-15-03875.jpg; http://eprints.unisza.edu.my/6685/2/FH02-FSK-15-04577.jpg; http://eprints.unisza.edu.my/6685/

Colorectal cancer (CRC) occurs as a more common sporadic form and a less common familial form. Our earlier analysis of germline mutations of mismatch repair genes confirmed only 32% of familial CRC cases as Lynch syndrome cases. It was hypothesized that the remaining familial aggregation may be ...