Comparison of Signal-to-noise, Blank Determination, and Linear Regression Methods for the Estimation of Detection and Quantification Limits for Volatile Organic Compounds by Gas Chromatography

Limit of detection (LOD) and limit of quantification (LOQ) are two important performance characteristics in method validation. This work compares three methods based on the International Conference of Harmonization (ICH) and EURACHEM guidelines, namely, signal-to-noise, blank determination, and line...

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Bibliographic Details

Main Authors:	Sanagi, Mohd Marsin, Ling, Susie L., Nasir, Zalilah, Hermawan, D., Wan Ibrahim, Wan Aini, Abu Naim, Ahmedy
Format:	Article
Language:	en
Published:	2008
Subjects:	QD Chemistry
Online Access:	http://eprints.utm.my/5670/2/MarsinSanagi20080604_Comparison_of_SNR_Blank_Regression.pdf http://eprints.utm.my/5670/
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