Automated platform for histological race and sex comparison of human cortical bone

Research on histological bone variation in population is in its early stages in Malaysia and limited information is available about age graded race and sex comparison. This research performed race and sex comparison of histological cortical bone parameters in the Malaysian population and presented a...

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Main Author: Abdullah, Hadi
Format: Thesis
Language:en
en
en
Published: 2019
Subjects:
Online Access:http://eprints.uthm.edu.my/63/1/24p%20HADI%20ABDULLAH.pdf
http://eprints.uthm.edu.my/63/2/HADI%20ABDULLAH%20WATERMARK.pdf
http://eprints.uthm.edu.my/63/3/HADI%20ABDULLAH%20COPYRIGHT%20DECLARATION.pdf
http://eprints.uthm.edu.my/63/
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_version_ 1833416429258407936
author Abdullah, Hadi
author_facet Abdullah, Hadi
author_sort Abdullah, Hadi
building UTHM Library
collection Institutional Repository
content_provider Universiti Tun Hussein Onn Malaysia
content_source UTHM Institutional Repository
continent Asia
country Malaysia
description Research on histological bone variation in population is in its early stages in Malaysia and limited information is available about age graded race and sex comparison. This research performed race and sex comparison of histological cortical bone parameters in the Malaysian population and presented an automated system which could be used as assistance tool by forensic experts. Human bone specimen were collected from Hospital Universiti Kebangsaan Malaysia Medical Centre (UKMMC), Kuala Lumpur, Malaysia. Haversian canals were measured and five parameters were calculated for comparison. Comparison test (t-test/u-test) showed that the size of Haversian canals were significantly greater (p<0.05) in females (HCM fifth, sixth decade: 5955.8 μm2, 5788.0 μm2) than males (HCM fifth, sixth decade: 4117.6 μm2, 3965.1 μm2). In race comparison, total area covered by Haversian canals (bone porosity) was significantly greater (p<0.05) in Indian samples (HCA: 0.457mm2) compared to Chinese samples (HCA: 0.385mm2) in the second decade. However in fifth decade, total area covered by Chinese samples (HCA: 0.894mm2) was significantly greater (p<0.05) than Indian samples (HCA: 0.570mm2). Three main steps of histological comparison were focused for automation i.e. parameter calculation, data management and statistical comparisons. The system was designed with GUI which utilizes aforementioned automation step. Validation of the system was divided into two main parts. In first part, parameter measurement and calculation performed by the system were compared with existing tools in terms of percentage error in measurement (DinoCapture: 5.3%, L-measure: 5.1%, ImageJ: 4.7%, designed system: 4.0%) and consumed time for measurement (DinoCapture: 15-20min, L-measure: 15-20min, ImageJ: 20-25min, designed system: 1-2min). Similarly automated race and sex comparison performed by the system were compared with comparisons performed manually using SPSS software. Significance and t/z values showed no differences and did not change overall hypothesis of the comparison tests. Which implies that the automated system is efficient for histological race and sex comparisons.
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publishDate 2019
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spelling my.uthm.eprints-632021-06-22T03:45:06Z http://eprints.uthm.edu.my/63/ Automated platform for histological race and sex comparison of human cortical bone Abdullah, Hadi QA76 Computer software Research on histological bone variation in population is in its early stages in Malaysia and limited information is available about age graded race and sex comparison. This research performed race and sex comparison of histological cortical bone parameters in the Malaysian population and presented an automated system which could be used as assistance tool by forensic experts. Human bone specimen were collected from Hospital Universiti Kebangsaan Malaysia Medical Centre (UKMMC), Kuala Lumpur, Malaysia. Haversian canals were measured and five parameters were calculated for comparison. Comparison test (t-test/u-test) showed that the size of Haversian canals were significantly greater (p<0.05) in females (HCM fifth, sixth decade: 5955.8 μm2, 5788.0 μm2) than males (HCM fifth, sixth decade: 4117.6 μm2, 3965.1 μm2). In race comparison, total area covered by Haversian canals (bone porosity) was significantly greater (p<0.05) in Indian samples (HCA: 0.457mm2) compared to Chinese samples (HCA: 0.385mm2) in the second decade. However in fifth decade, total area covered by Chinese samples (HCA: 0.894mm2) was significantly greater (p<0.05) than Indian samples (HCA: 0.570mm2). Three main steps of histological comparison were focused for automation i.e. parameter calculation, data management and statistical comparisons. The system was designed with GUI which utilizes aforementioned automation step. Validation of the system was divided into two main parts. In first part, parameter measurement and calculation performed by the system were compared with existing tools in terms of percentage error in measurement (DinoCapture: 5.3%, L-measure: 5.1%, ImageJ: 4.7%, designed system: 4.0%) and consumed time for measurement (DinoCapture: 15-20min, L-measure: 15-20min, ImageJ: 20-25min, designed system: 1-2min). Similarly automated race and sex comparison performed by the system were compared with comparisons performed manually using SPSS software. Significance and t/z values showed no differences and did not change overall hypothesis of the comparison tests. Which implies that the automated system is efficient for histological race and sex comparisons. 2019-06 Thesis NonPeerReviewed text en http://eprints.uthm.edu.my/63/1/24p%20HADI%20ABDULLAH.pdf text en http://eprints.uthm.edu.my/63/2/HADI%20ABDULLAH%20WATERMARK.pdf text en http://eprints.uthm.edu.my/63/3/HADI%20ABDULLAH%20COPYRIGHT%20DECLARATION.pdf Abdullah, Hadi (2019) Automated platform for histological race and sex comparison of human cortical bone. Doctoral thesis, Universiti Tun Hussein Onn Malaysia.
spellingShingle QA76 Computer software
Abdullah, Hadi
Automated platform for histological race and sex comparison of human cortical bone
title Automated platform for histological race and sex comparison of human cortical bone
title_full Automated platform for histological race and sex comparison of human cortical bone
title_fullStr Automated platform for histological race and sex comparison of human cortical bone
title_full_unstemmed Automated platform for histological race and sex comparison of human cortical bone
title_short Automated platform for histological race and sex comparison of human cortical bone
title_sort automated platform for histological race and sex comparison of human cortical bone
topic QA76 Computer software
url http://eprints.uthm.edu.my/63/1/24p%20HADI%20ABDULLAH.pdf
http://eprints.uthm.edu.my/63/2/HADI%20ABDULLAH%20WATERMARK.pdf
http://eprints.uthm.edu.my/63/3/HADI%20ABDULLAH%20COPYRIGHT%20DECLARATION.pdf
http://eprints.uthm.edu.my/63/
url_provider http://eprints.uthm.edu.my/