Pathophysiology, histopathology and therapeutic of SARS-CoV-2

The rapid transmission of SARS-CoV-2 through the world has induced the scientist to understand the histopathology of the virus and then to find an effective drug. However, many of the point associated with the virus pathogenicity still unknown and need more studies. In this chapter the pathophysiolo...

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Main Authors: Noman, Efaq, Al-Gheethi, Adel, Radin Mohamed, Radin Maya Saphira, Al-Shorgani, Najeeb, Talip, Balkis, Hezam, Kamal, Othman, Norzila
Other Authors: Al-Gheethi, Adel Ali Saeed
Format: Book Section
Language:en
Published: Penerbit UTHM 2020
Subjects:
Online Access:http://eprints.uthm.edu.my/2255/1/ch04.pdf
http://eprints.uthm.edu.my/2255/
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author Noman, Efaq
Al-Gheethi, Adel
Radin Mohamed, Radin Maya Saphira
Al-Shorgani, Najeeb
Talip, Balkis
Hezam, Kamal
Othman, Norzila
author2 Al-Gheethi, Adel Ali Saeed
author_facet Al-Gheethi, Adel Ali Saeed
Noman, Efaq
Al-Gheethi, Adel
Radin Mohamed, Radin Maya Saphira
Al-Shorgani, Najeeb
Talip, Balkis
Hezam, Kamal
Othman, Norzila
author_sort Noman, Efaq
building UTHM Library
collection Institutional Repository
content_provider Universiti Tun Hussein Onn Malaysia
content_source UTHM Institutional Repository
continent Asia
country Malaysia
description The rapid transmission of SARS-CoV-2 through the world has induced the scientist to understand the histopathology of the virus and then to find an effective drug. However, many of the point associated with the virus pathogenicity still unknown and need more studies. In this chapter the pathophysiology, histopathology and therapeutic of SARS-CoV-2 has been reviewed. It was appeared that pathogenicity of SARS-CoV-2 is belonging to the viral with genome structure which acting by blocking the host innate immune response. Both chloroquine and hydroxyl-chloroquine have similar structure and mechanism action and they are among the most effective antiviral for treating the patents with the SARS-CoV-2. Chloroquine works by inhibition the intracellular organism by increasing the pH.
format Book Section
id my.uthm.eprints-2255
institution Universiti Tun Hussein Onn Malaysia
language en
publishDate 2020
publisher Penerbit UTHM
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spelling my.uthm.eprints-22552021-11-02T03:47:46Z http://eprints.uthm.edu.my/2255/ Pathophysiology, histopathology and therapeutic of SARS-CoV-2 Noman, Efaq Al-Gheethi, Adel Radin Mohamed, Radin Maya Saphira Al-Shorgani, Najeeb Talip, Balkis Hezam, Kamal Othman, Norzila RA Public aspects of medicine The rapid transmission of SARS-CoV-2 through the world has induced the scientist to understand the histopathology of the virus and then to find an effective drug. However, many of the point associated with the virus pathogenicity still unknown and need more studies. In this chapter the pathophysiology, histopathology and therapeutic of SARS-CoV-2 has been reviewed. It was appeared that pathogenicity of SARS-CoV-2 is belonging to the viral with genome structure which acting by blocking the host innate immune response. Both chloroquine and hydroxyl-chloroquine have similar structure and mechanism action and they are among the most effective antiviral for treating the patents with the SARS-CoV-2. Chloroquine works by inhibition the intracellular organism by increasing the pH. Penerbit UTHM Al-Gheethi, Adel Ali Saeed Radin Mohamed, Radin Maya Saphira Ali Noman, Efaq 2020 Book Section PeerReviewed text en http://eprints.uthm.edu.my/2255/1/ch04.pdf Noman, Efaq and Al-Gheethi, Adel and Radin Mohamed, Radin Maya Saphira and Al-Shorgani, Najeeb and Talip, Balkis and Hezam, Kamal and Othman, Norzila (2020) Pathophysiology, histopathology and therapeutic of SARS-CoV-2. In: Covid-19 Pandemic. Penerbit UTHM, pp. 64-76. ISBN 978-967-2389-64-4
spellingShingle RA Public aspects of medicine
Noman, Efaq
Al-Gheethi, Adel
Radin Mohamed, Radin Maya Saphira
Al-Shorgani, Najeeb
Talip, Balkis
Hezam, Kamal
Othman, Norzila
Pathophysiology, histopathology and therapeutic of SARS-CoV-2
title Pathophysiology, histopathology and therapeutic of SARS-CoV-2
title_full Pathophysiology, histopathology and therapeutic of SARS-CoV-2
title_fullStr Pathophysiology, histopathology and therapeutic of SARS-CoV-2
title_full_unstemmed Pathophysiology, histopathology and therapeutic of SARS-CoV-2
title_short Pathophysiology, histopathology and therapeutic of SARS-CoV-2
title_sort pathophysiology, histopathology and therapeutic of sars-cov-2
topic RA Public aspects of medicine
url http://eprints.uthm.edu.my/2255/1/ch04.pdf
http://eprints.uthm.edu.my/2255/
url_provider http://eprints.uthm.edu.my/