3,5-Bis(arylidene)-4-piperidones as potential dengue protease inhibitors

Dengue is a severe mosquito-borne viral in fection causing half a million deaths annually. Dengue virusNS2B/NS3 protease is a validated target for anti-dengue drug design. A series of hitherto unreported 3,5-bis(arylidene)-4-piperidones analogues 4a–4j were synthesized and screened in silico against...

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Bibliographic Details

Main Authors:	Osman, Hasnah, Idris, Nor Hashima, Kamarulzaman, Ezatul Ezleen, A. Wahab, Habibah, Hassan, Mohd. Zaheen
Format:	Article
Published:	Elsevier 2017
Subjects:	QD1-999 Chemistry RS1-441 Pharmacy and materia medica
Online Access:	http://eprints.usm.my/37959/ http://dx.doi.org/10.1016/j.apsb.2017.04.009
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