3,5-Bis(arylidene)-4-piperidonesaspotential dengue proteaseinhibitors

Dengue isaseveremosquito-borneviralinfectioncausinghalfamilliondeathsannually. Dengue virusNS2B/NS3proteaseisavalidatedtargetforanti-denguedrugdesign.Aseriesofhitherto unreported 3,5-bis(arylidene)-4-piperidonesanalogues 4a–4j were synthesizedandscreened in silico against DENV2NS2B/NS3proteasetoe...

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Bibliographic Details

Main Authors:	Osman, Hasnah, Idris, Nor Hashima, Kamarulzaman, Ezatul Ezleen, A.Wahab, Habibah, Hassan, Mohd. Zaheen
Format:	Article
Published:	Elsevier 2017
Subjects:	RS1-441 Pharmacy and materia medica
Online Access:	http://eprints.usm.my/36660/ http://dx.doi.org/10.1016/j.apsb.2017.04.009
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