Synthesis, in-vivo anti-diabetic & anticancer activities and molecular modelling studies of tetrahydro benzo[d]thiazole tethered nicotinohydrazide derivatives

A series of thirty new thiazole-pyridine derivatives were synthesized by reaction of 4,4,7,7-tetra-methyl-4,5,6,7-tetrahydrobenzo[d]thiazol-2-amine with 6-chloronicotinate followed by condensing with benzaldehydes and screened for their anti-diabetic activity by in vivo housing Swiss albino mice. Al...

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Main Authors:	Suri Babu Patchipala, Visweswara Rao Pasupuleti, Amrutha V Audipudi, Hari babu Bollikolla
Format:	Article
Language:	en en
Published:	King Saud University 2021
Subjects:	RC254-282 Neoplasms. Tumors. Oncology Including cancer and carcinogens RC31-1245 Internal medicine
Online Access:	https://eprints.ums.edu.my/id/eprint/33239/1/Synthesis%2C%20in-vivo%20anti-diabetic%20%26%20anticancer%20activities%20and%20molecular%20modelling%20studies%20of%20tetrahydro%20benzo%5Bd%5Dthiazole%20tethered%20nicotinohydrazide%20derivatives.pdf https://eprints.ums.edu.my/id/eprint/33239/2/Synthesis%2C%20in-vivo%20anti-diabetic%20%26%20anticancer%20activities%20and%20molecular%20modelling%20studies%20of%20tetrahydro%20benzo%5Bd%5Dthiazole%20tethered%20nicotinohydrazide%20derivatives1.pdf https://eprints.ums.edu.my/id/eprint/33239/ https://www.sciencedirect.com/science/article/pii/S187853522100561X https://doi.org/10.1016/j.arabjc.2021.103546
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