Physicochemical characterization, molecular docking, and in vitro dissolution of glimepiride–captisol inclusion complexes

This present study investigated the effect of Captisol, a chemically modified cyclodextrin, on the in vitro dissolution of glimepiride. We prepared glimepiride–Captisol complexes of different mass ratios (1:1, 1:2, and 1:3 w/w) by a physical mixing or freeze-drying technique, and found that complexa...

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Bibliographic Details

Main Authors:	Pal, Arpita, Roy, Sudeep, Kumar, Akhil, Mahmood, Syed, Nasrin, Khodapanah, Thomas, Sabu, Agatemor, Christian, Ghosal, Kajal
Format:	Article
Language:	en
Published:	American Chemical Society 2020
Subjects:	TP Chemical technology
Online Access:	http://umpir.ump.edu.my/id/eprint/31392/1/Physicochemical%20characterization%20molecular%20docking%2C%20and%20in%20vitro%20dissolution.pdf http://umpir.ump.edu.my/id/eprint/31392/ https://doi.org/10.1021/acsomega.0c01228
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