Lumbar puncture in children with acute lyhmphoblastic leukaemia / Noor Hidayah Saarey@Ghazali

Title : Lumbar puncture in children with acute lymphoblastic leukaemia. Introduction : Acute lymphoblastic leukaemia (ALL) is the most common malignancy diagnosed in children, representing more than a quarter of all paed iatric cancers. Lumbar puncture (LP) is a diagnostic and therapeutic clinical p...

Full description

Saved in:
Bibliographic Details
Main Author: Noor Hidayah, Saarey@Ghazali
Format: Thesis
Published: 2017
Subjects:
Online Access:http://studentsrepo.um.edu.my/13357/1/Noor_Hidayah_Saarey@Ghazali.pdf
http://studentsrepo.um.edu.my/13357/
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1831436263295549440
author Noor Hidayah, Saarey@Ghazali
author_facet Noor Hidayah, Saarey@Ghazali
author_sort Noor Hidayah, Saarey@Ghazali
building UM Library
collection Institutional Repository
content_provider Universiti Malaya
content_source UM Student Repository
continent Asia
country Malaysia
description Title : Lumbar puncture in children with acute lymphoblastic leukaemia. Introduction : Acute lymphoblastic leukaemia (ALL) is the most common malignancy diagnosed in children, representing more than a quarter of all paed iatric cancers. Lumbar puncture (LP) is a diagnostic and therapeutic clinical procedure in paediatric oncology. Diagnostically, LP is routinely performed to detect the existence of cancer cells in the cerebrospinal fluid (CSF) whilst therapeutically, lumbar puncture is performed to deliver intrathecal chemotherapy. For the past 6 years, Ma-Spore ALL 2010 protocol have been used in University Malaya Medical Centre (UMMC), for the treatment of paediatric acute lymphoblast leukaemia (ALL) based-on patient risk stratification, which involved diagnostic and multiple therapeutic LP. The aim of this study is to identify the prevalence or performing successful LP in single attempt, risk factors associated with it, to describe the complications related to lumbar puncture and sedation used. This study also aim to identify the prevalence of parental reluctance in giving consent for their children first LP and whether they needed re-consenting/re-explanation for subsequent LPs, as well as to identify the relationship between parental reluctance and need for reconsenting and their psychosocial background. Another aim of this study is to validate a previous formula used for an ideal depth of needle insertion for a successful LP (Chong, 2009).
format Thesis
id my.um.stud-13357
institution Universiti Malaya
publishDate 2017
record_format eprints
spelling my.um.stud-133572025-04-28T17:41:26Z Lumbar puncture in children with acute lyhmphoblastic leukaemia / Noor Hidayah Saarey@Ghazali Noor Hidayah, Saarey@Ghazali R Medicine (General) RJ Pediatrics Title : Lumbar puncture in children with acute lymphoblastic leukaemia. Introduction : Acute lymphoblastic leukaemia (ALL) is the most common malignancy diagnosed in children, representing more than a quarter of all paed iatric cancers. Lumbar puncture (LP) is a diagnostic and therapeutic clinical procedure in paediatric oncology. Diagnostically, LP is routinely performed to detect the existence of cancer cells in the cerebrospinal fluid (CSF) whilst therapeutically, lumbar puncture is performed to deliver intrathecal chemotherapy. For the past 6 years, Ma-Spore ALL 2010 protocol have been used in University Malaya Medical Centre (UMMC), for the treatment of paediatric acute lymphoblast leukaemia (ALL) based-on patient risk stratification, which involved diagnostic and multiple therapeutic LP. The aim of this study is to identify the prevalence or performing successful LP in single attempt, risk factors associated with it, to describe the complications related to lumbar puncture and sedation used. This study also aim to identify the prevalence of parental reluctance in giving consent for their children first LP and whether they needed re-consenting/re-explanation for subsequent LPs, as well as to identify the relationship between parental reluctance and need for reconsenting and their psychosocial background. Another aim of this study is to validate a previous formula used for an ideal depth of needle insertion for a successful LP (Chong, 2009). 2017 Thesis NonPeerReviewed application/pdf http://studentsrepo.um.edu.my/13357/1/Noor_Hidayah_Saarey@Ghazali.pdf Noor Hidayah, Saarey@Ghazali (2017) Lumbar puncture in children with acute lyhmphoblastic leukaemia / Noor Hidayah Saarey@Ghazali. Masters thesis, Universiti Malaya. http://studentsrepo.um.edu.my/13357/
spellingShingle R Medicine (General)
RJ Pediatrics
Noor Hidayah, Saarey@Ghazali
Lumbar puncture in children with acute lyhmphoblastic leukaemia / Noor Hidayah Saarey@Ghazali
title Lumbar puncture in children with acute lyhmphoblastic leukaemia / Noor Hidayah Saarey@Ghazali
title_full Lumbar puncture in children with acute lyhmphoblastic leukaemia / Noor Hidayah Saarey@Ghazali
title_fullStr Lumbar puncture in children with acute lyhmphoblastic leukaemia / Noor Hidayah Saarey@Ghazali
title_full_unstemmed Lumbar puncture in children with acute lyhmphoblastic leukaemia / Noor Hidayah Saarey@Ghazali
title_short Lumbar puncture in children with acute lyhmphoblastic leukaemia / Noor Hidayah Saarey@Ghazali
title_sort lumbar puncture in children with acute lyhmphoblastic leukaemia / noor hidayah saarey@ghazali
topic R Medicine (General)
RJ Pediatrics
url http://studentsrepo.um.edu.my/13357/1/Noor_Hidayah_Saarey@Ghazali.pdf
http://studentsrepo.um.edu.my/13357/
url_provider http://studentsrepo.um.edu.my/