New synthetic phenylquinazoline derivatives induce apoptosis by targeting the pro-survival members of the BCL-2 family

Chemo-resistant cancer cells acquire robust growth potential through cell signaling mechanisms such as the down-regulation of tumor suppressors and the up-regulation of pro-survival proteins, respectively. To overcome chemo-resistance of cancer, small molecule drugs that interact with the cell signa...

Full description

Bibliographic Details

Main Authors:	Simon, Samson Eugin, Usman, Ahmed *, Saad, Syed Muhammad, Ayaz, Anwar *, Khan, Khalid Mohammed, Tan, Ee Wern *, Tan, Kuan Onn *
Format:	Article
Published:	Elsevier 2022
Subjects:	QH Natural history RC Internal medicine RM Therapeutics. Pharmacology
Online Access:	http://eprints.sunway.edu.my/3113/ https://doi.org/10.1016/j.bmcl.2022.128731
Tags:	Add Tag No Tags, Be the first to tag this record!