Computational design strategy of pharmaceutical co-crystals: A case study of anti-cancer drugs / Nadia Hanim Sabri
Thymidylate synthase (TS) is a biomarker for fluoropyrimidine-based chemotherapy that provides the sole intracellular de novo source of thymidylate, an essential precursor to DNA synthesis. Antifolate drug and fluoropyrimidine-based drug have potential to disrupt TS activity by nucleotide and ant...
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| Format: | Thesis |
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2018
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| Online Access: | http://studentsrepo.um.edu.my/9593/1/Nadia_Hanim_Sabri.pdf http://studentsrepo.um.edu.my/9593/6/nadia_hanim.pdf http://studentsrepo.um.edu.my/9593/ |
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