Dysregulation of the orexinergic system: A potential neuropeptide target in depression

Orexins are highly involved in regulating the circadian rhythm, the brain's reward mechanism, and the neuroendocrine response to stress. The disruption of orexin regulation is known to be associated with depression. Preclinical studies in rodents have identified the dorsomedial/perifornical and...

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Bibliographic Details
Main Authors: Khairuddin, Sharafuddin, Aquili, Luca, Heng, Boon Chin, Hoo, Tze Lok Cecil, Wong, Kah Hui, Lim, Lee Wei
Format: Article
Published: Elsevier 2020
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Online Access:http://eprints.um.edu.my/36294/
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