Solubility enhancement of statin-based molecules by arginine: thermodynamics, solute-solvent interaction and solid state characterization / Meor Mohd Redzuan Meor Mohd Affandi

• Main Author: Meor Mohd Affandi, Meor Mohd Redzuan
• Format: Book Section
• Language: English
• Published: Institute of Graduate Studies, UiTM 2016
• Subjects: Malaysia
• Online Access: http://ir.uitm.edu.my/id/eprint/19924/1/ABS_MEOR%20MOHD%20REDZUAN%20MEOR%20MOHD%20AFFANDI%20TDRA%20VOL%2010%20IGS%2016.pdf; http://ir.uitm.edu.my/id/eprint/19924/

Categorized as a Biopharmaceutics Classification System (BCS) Class II drugs, statins exhibit low aqueous solubility and bioavailability thus presenting an obstacle and great challenge to formulation researchers. As a consequence, abundant studies are available in regard to the solubility enhancemen...