Cationic liposome- multi-walled carbon nanotubes hybrids for dual siPLK1 and doxorubicin delivery in vitro

• Main Authors: Pereira, Sara, Lee, Jin, Rubio, Noelia, Hassan, Hatem A. F. M., Mohamed Suffian, Izzat Fahimuddin, Wang, Julie Tzu-Wen, Klippstein, Rebecca, Ballesteros, Belén, Al-Jamal, Wafa, Al-Jamal, Khuloud
• Format: Article
• Language: English
• Published: Springer US 2015
• Subjects: RM Therapeutics. Pharmacology; RM300 Drugs and their action; RS Pharmacy and materia medica
• Online Access: http://irep.iium.edu.my/57363/1/Pereira_Pharm_Res_2015.pdf; http://irep.iium.edu.my/57363/; http://dx.doi.org/10.1007/s11095-015-1707-1

PURPOSE: To formulate f-MWNTs-cationic liposome hybrids for the simultaneous delivery of siPLK1 and doxorubicin to cancer cells. METHOD: f-MWNTs-cationic liposome hybrids were prepared by the thin film hydration method where the lipid film was hydrated with 100 μg/ml or 1 mg/ml of ox-MWNTs-NH3 (+)...